ICMR-National Institute for Research in Bacterial Infections has developed a technology that can help develop a vaccine from outer membrane structures of the Typhoid causing pathogen
The National Institute for Research in Bacterial Infections based in Kolkata which is one of the premier institutes under the Indian Council of Medical Research is working on vaccines for typhoid and paratyphoid. It has invited proposals from private sector companies for this.
The institute has developed a technology entitled “Enteric fever vaccine based on Outer membrane Vesicles from two different strains of Typhoidal Salmonelle species”. The bacteria that causes typhoid is known as Salmonella typhi. In a public notice inviting interest, the council has said that it is willing to collaborate with eligible organizations, companies, and manufacturers for undertaking validation, joint development and commercialization of a broad specificity vaccine that works in typhoid and paratyphoid.
Intellectual property rights would jointly belong to ICMR and the chosen private partner. Data would belong to ICMR
“ ICMR-NIRBI Institute will provide expert guidance & technical support for the production of Typhoid & Paratyphoid vaccine in all phases. Such technical oversight by ICMR-NIRBI Institute would accelerate the development of the Product and its commercialization. ICMR would provide technical support through its team of experienced scientists in study planning, product development, development of study protocol, results/data analysis, outcome assessment, safety & efficacy assessment, product improvement, etc., if deemed fit upon the mutual understanding between ICMR and collaborative company,” the notice inviting expressions of interest from private parties reads.
Typhoid is a water or food borne infection that is characterised by fever, loss of appetite, nausea, altered bowel movements etc. The topmost causes of the infection are poor sanitation and lack of clear drinking water. Paratyphoid which is caused by the Salmonella paratyphi bacteria also has similar symptoms.
For the vaccine, if developed, intellectual property rights would jointly belong to ICMR and the chosen private partner. Data would belong to ICMR provided the government organisation provides 100% funding.