Severe anemia among most used PMJAY packages; reflects poorly on Anemia Mukt Bharat plan

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The purpose of a truly integrated health system is to prevent catastrophic health spends through primary care interventions

Since 2018 when the Ayushman Bharat – Pradhan Mantri Jan Arogya Yojana was launched, 4,14,167 people have been  hospitalised with severe anemia. Treatments for severe anemia can include blood transfusions, iron injections, IV iron therapy or hormonal therapy. 

As it happens, 2018 was also the year when the government of India launched the Anemia Mukt Bharat programme under which prophylactic iron and folic acid supplementation, supply of fortified foods etc are done to young children, adolescents of either sex, women of reproductive age and expecting and lactating mothers. It is a scheme that tries to deliver the most basic common sense anti anemia interventions to the groups most vulnerable to it. All of these interventions are deliverable at the level of the primary health centre or even at home by the ASHA workers during one of her field visits.

PMJAY on the other hand provides support only for hospitalisation, that is it is a scheme for making secondary and tertiary healthcare available to the poorest of the poor without landing them in bankruptcy. The fact that such a large number of people have landed in hospital in the last six years needing  secondary and tertiary care shows that Ayushman Bharat has failed to deliver as a fully functioning health system with 1,53000 health and wellness centres delivering primary care and ensuring wellness while PMJAY – which provides and annual health insurance if Rs 5 lakh per eligible family – takes care of the inevitable hospitalisation expenses. The idea of clubbing preventive and promotive healthcare with tertiary care is to ensure that conditions that can be dealt with through low cost interventions – in this case iron, folic acid, fortified foods etc – do not go on to become catastrophic health spends.

Unfortunately not only do the two arms of the Ayushman Bharat programme not talk to each other, the review of each is done independent of the other when reality is that it is only as a whole that this can truly make sense. On Friday when health minister J P Nadda undertook a review of PMJAY he was told  that  34.7 crore Ayushman cards have been created and more than 7.35 crore hospital admissions amounting to more than 1 lakh crore have been provided under the scheme. But unless review processes go beyond numbers the true functional utility of schemes can never be assessed. 

India’s anaemia problem of course has many facets, one of which is the recent eulogisation of vegetarianism. Protein intake is crucial for the formation of haemoglobin which is a compound made of an iron derivative – haem – and protein. But in a country where serving eggs in school meal programmes are becoming increasingly political, the incidence of anemia is  unlikely to go down significantly merely with nutritional supplements. According to NFHS 5 data, 67.1% of Indian children aged less than 5 years are anemic, as are 52.2% pregnant women. Overall 25% men and 57% women are anemic.

56% Indian women have access to modern contraception, family planning focus shifts to districts

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On World Population Day government of India takes stock; Mission Parivar Vikas has been extended to 340 districts 

The latest family health survey shows that 56.5% of Indian women of reproductive age now have access to modern contraceptives. The ministry of health and family welfare has decided to shift the focus of family planning efforts – Mission Parivar Vikas – to the districts, health minister J P Nadda said Thursday.

“The objective of the FP programme needs to be ‘Birth by choice and by informed choice,”  Nadda said on the occasion of World Population Day.  Highlighting the government’s focus on “securing a brighter, healthier future for all, including youth, adolescents, women, and the elderly”, the Union Health Minister stated, “collaboration is key as we address upcoming responsibilities and recognize family planning and reproductive health as fundamental”. “Promoting healthy timing and spacing between births, achieving optimal family sizes, and empowering voluntary adoption of contraceptive choices are crucial for nurturing healthier and happier families, thereby contributing to our nation’s brighter future”, he said.

An innovative Family Planning Display Model “Sugam” and family planning posters in Hindi, English, and regional languages imbibing the current year’s theme for World Population Day 2024 were unveiled. Sugam is a unique and innovative multipurpose display model for Family Planning designed for use by family planning service providers, RMNCHA (Reproductive, Maternal, Newborn, Child, Adolescent Health and Nutrition) counsellors, grassroots health workers, and beneficiaries. 

It can also be strategically displayed at various locations at health facilities. ‘Sugam’ aims to foster an amicable environment and generate necessary awareness about family planning. It envisaged creating the necessary buzz around equal participation of men and women in family planning, encouraging planned parenthood, emphasizing healthy timing and spacing between births, and showcasing the range of contraceptive choices available. Newly developed Radio Spots and Jingles aimed at creating awareness about family planning and increasing uptake of family planning commodities were also launched.

“It is also encouraging to note that the acceptance of modern contraceptives in the country has increased to over 56%. NFHS 5 data shows an overall positive shift towards spacing methods which would be instrumental in impacting positively the maternal and infant mortality and morbidity. The Unmet Need for Family Planning has declined to 9.4 from 12.9 (NFHS IV) which is an encouraging achievement”, minister of state Anupriya Patel said.

Eating small fish may result in big gains in longevity, report Japanese scientists

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Fish such as whitebait, Atlantic capelin, Japanese smelt, and small dried sardines, often consumed whole, are rich in calcium and vitamin A

Japanese scientists have reported that eating small fish whole (witn bones and internal organs) may come with big gains in longevity. It also seems to reduce cancer mortality.

Dr. Chinatsu Kasahara, Associate Professor Takashi Tamura, and Professor Kenji Wakai at Nagoya University Graduate School of Medicine in Japan have reported their findings in the journal  Public Health Nutrition. Fish such as whitebait, Atlantic capelin, Japanese smelt, and small dried sardines, often consumed whole, are rich in calcium and vitamin A

The research team investigated the association between the intake of small fish and mortality risk among Japanese people. The study included 80,802 participants (34,555 men and 46,247 women) aged 35 to 69 years nationwide in Japan. The participants’ frequency of the intake of small fish was assessed using a food frequency questionnaire at baseline. The researchers followed them for an average of nine years. During the follow-up period, 2,482 deaths from people included in the study were recorded, with approximately 60% (1,495 deaths) of them being cancer related. 

One of the most striking findings of the study was the significant reduction in all-cause and cancer mortality among women who habitually eat small fish. 

“Previous studies have revealed the protective effect of fish intake on health outcomes, including mortality risks. However, few studies have focused on the effect of the intake of small fish specifically on health outcomes,” said the lead researcher, Dr. Kasahara. “I was interested in this topic because I have had the habit of eating small fish since childhood. I now feed my children these.” 

The research team investigated the association between the intake of small fish and mortality risk among Japanese people. The study included 80,802 participants (34,555 men and 46,247 women) aged 35 to 69 years nationwide in Japan. The participants’ frequency of the intake of small fish was assessed using a food frequency questionnaire at baseline. The researchers followed them for an average of nine years. During the follow-up period, 2,482 deaths from people included in the study were recorded, with approximately 60% (1,495 deaths) of them being cancer related. 

 

The “carcinogenicity” of the key baby powder ingredient may change the way we look at talcum

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Talc or talcum has been linked to ovarian cancer; in animal studies it has also been associated with a higher risk of lung cancer and for derailing the cell growth mechanisms

A Working Group of 29 scientists from 13 countries under the aegis of the International Agency for Research on Cancer (IARC) have sounded the alarm

Talc, which is a mineral that is commonly used in baby powders, may be carcinogenic, a working group under the aegis of the International Agency for Research on Cancer (IARC) has concluded. 

In their findings published in The Lancet Oncology, the group had sounded the alarm on “talc,” defining it as mineral or synthetic talc, a hydrated magnesium silicate, including lamellar and fibrous (which includes asbestiform fibres) forms of talc. They found “limited evidence” that talc causes ovarian cancer in humans. They also found links to inflammation, some forms of lung cancer in animal studies and a role in altering cell proliferation, cell death, or nutrient supply all of which can lead to cancerous growth in the body. 

Following the report of the group, the IARC has classified talc (with or without asbestos contamination) as a Group 2A classified carcinogen. Group 2A classification means it is the second highest level of certainty of that substance causes cancer.

“There were numerous studies that consistently showed an increase in the incidence of ovarian cancer in humans self-reporting the use of body powder in the perineal region. Although the evaluation focused on talc not containing asbestos, contamination of talc with asbestos could not be excluded in most of the studies of exposed humans. In addition, biases in how talc use was reported in the epidemiological studies could not be ruled out with reasonable confidence. As a result, a causal role for talc could not be fully established. An increased rate of ovarian cancer was also observed in studies looking at occupational exposure of women exposed to talc in the pulp and paper industry. However, confounding by co-exposure to asbestos could not be excluded, and the increased rate was based on small numbers of ovarian cancers in those occupational studies,” IARC said.

Why FSSAI wants salt, sugar and saturated fat content prominently displayed 

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FSSAI has mandated that packaged food items will now have to display information about certain ingredients prominently. Here’s why.

In a decision that the government hopes will spur Indians towards healthier food choices, the Food Safety and Standards Authority of India recently mandated that packaged foods have to display salt, sugar and unsaturated fat content in bold, bigger font in the packs.

Why has the FSSAI singled out these three ingredients as the main villains in India’s fight against non communicable diseases? Medibulletin brings you an overview.

Salt

Salt is a crucial component of the body’s internal milieu. Both an increase and a decrease in the level of salt, no matter how minute can throw bodily processes off gear. That is why a dip in sodium (common salt is a mixture of sodium and chloride) is associated with such dramatic symptoms such as delirium that gets corrected as the electrolyte levels rise. But long term intake of high levels of salt is associated with a rise in blood pressure, kidney problems or even cancer.

According to the World Health Organisation: “The primary health effect associated with diets high in sodium is raised blood pressure, increasing the risk of cardiovascular diseases, gastric cancer, obesity, osteoporosis, Meniere’s disease, and kidney disease. An estimated 1.89 million deaths each year are associated with consuming too much sodium.” Chips, sandwiches and most savoury snacks are high in salt content.

Sugar

Of all the three items the ill effects of sugar are probably best known. Sugar is associated with obesity, some theories suggest it is addictive – the more sugar a person eats the more they crave it. But eating sugar does not cause diabetes. Diabetes is a metabolic disease that hampers the body’s ability to process carbohydrates – commonly referred to as sugar. An article published by the Harvard Medical School summed up the vagaries of sugar thus. “Consuming too much added sugar can raise blood pressure and increase chronic inflammation, both of which are pathological pathways to heart disease. Excess consumption of sugar, especially in sugary beverages, also contributes to weight gain by tricking your body into turning off its appetite-control system because liquid calories are not as satisfying as calories from solid foods. This is why it is easier for people to add more calories to their regular diet when consuming sugary beverages,” it said.

Saturated fat

Saturated fats are a class of fats found in butter, cheese, poultry and red meat. They are associated with increased risk of high cholesterol, which in its turn can clog the blood vessels and lead to heart problems. The American Heart Association recommends that about  5% to 6% of the daily calories of an individual can come from saturated fat.

For a diet of 2,000 calories a day, 120 calories can come from saturated fat- that is 13 grams per day.

 

Stay off processed meats such as sausages and soft drinks, advices American Society of Nutrition

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Some processed foods, the society said in a statement, may have a great association with mortality risk than others

While the risks of ultra processed foods are well known, some of them may be more harmful than others. The American Society of Nutrition has identified sausages, hot dogs and deli meat as some of the more harmful products in the ultraprocessed category. 

The findings were presented at NUTRITION 2024, the flagship annual meeting of the American Society for Nutrition held in Chicago earlier this month. The findings are based on a large study that has tracked over half a million U.S. adults for nearly three decades. According to the results, higher intake of ultra-processed foods was associated with modest increases in death from any cause and from deaths related specifically to heart disease or diabetes, but no association was found for cancer-related deaths.

“Our study results support a larger body of literature, including both observational and experimental studies, which indicate that ultra-processed food intake adversely impacts health and longevity,” said Erikka Loftfield, PhD, Stadtman Investigator at the National Cancer Institute. “However, there is still a lot that we don’t know, including what aspects of ultra-processed foods pose potential health risks.”

According to a recent 30-year study published in The BMJ, ultraprocessed foods such as (but not limited to) sweetened breakfast ‘cereals’ and fruit yoghurt and ‘energy’ drinks; pre-prepared meat, cheese, pasta and pizza can shorten a person’s life. 

The present research drew data from more than 540,000 people who provided information about their eating habits and health in the mid-1990s, when they were between 50 and 71 years of age. Over half of the participants have since died. The researchers analyzed overall rates of death among those who were in the 90th percentile for consumption of ultra-processed foods at baseline versus those in the 10th percentile, and also looked at associations with specific foods and specific diseases. 

What is hydrogen peroxide nebulisation that has caused the Liverdoc-Samantha Ruth face-off

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A set of unusual antagonists – a doctor and an actor – have been arguing about a medical procedure. Here’s all you need to know about it

 

Over the last few days, Dr. Cyriac Abby Philips, better known by his social media moniker of ‘The Liver Doc,’ and film star Samantha Ruth Prabhu have been arguing about a medical procedure – hydrogen peroxide nebulisation.

When Prabhu had advocated it in one of her posts, Dr Philips called her “health and science illiterate” triggering a war of words between the two unlikely adversaries. For many onlookers, the process itself and what it is used for, have remained an enigma as the focus remains on the face-off. Medibulletin takes you through it.

What is hydrogen peroxide nebulisation?

Hydrogen peroxide is a commonly used disinfectant used in medical setups, ambulances and to clean equipment. The trend using it in a nebuliser emerged around the time of the COVID19 pandemic causing alarm among many sections of doctors. The Asthma and Allergy Foundation of America had issued a statement that said: “Hydrogen peroxide can be used as a cleaner and stain remover, and can cause tissue damage if you swallow it or breathe it in…A nebulizer is a “breathing machine” used to treat asthma. It turns liquid asthma medicine into a mist. You then breathe in the medicine through a mask or mouthpiece. Only use asthma medicine prescribed by your doctor in your nebulizer. Other chemicals can be harmful to your lungs.” 

What is Samantha using it for?

In her original controversial post, Samantha wrote: “Before taking medication for a common viral, consider trying an alternative approach. One option is to nebulize with a mixture of hydrogen peroxide and distilled water. Works like magic. Avoid unnecessary use of tablets #alternative medicine @dr_mitra_basu_chhillar (sic).” She had tagged her doctor in the post.

What are the risks of using hydrogen peroxide in a nebulliser?

According to the Agency for Toxic Substances and Disease Registry that says that the compound can be toxic if ingested, inhaled, or by contact with the skin or eyes. If it is inhaled or nebulised in diluted form it can lead to severe irritation of the lungs. The AAA statement was referenced by Dr Philips in his post where he slammed the actor for her misleading advice. “A rational and logical response would be to delete the public health endangering posts and apologize to her millions of followers and vouch to never quote or cite fraudulent practices or practitioners. 

 

I have absolutely ZERO hope for improving scientific temperament or rationalism in this country. Everyone role plays the victim of “scientific criticism” but will keep embracing and holding on to dogmatic views in healthcare, traditional untested observations or debunked dangerous therapies without shame or self reflection,” he wrote in a post on X.

 

Salt, sugar and saturated fat content will now be displayed in bold, bigger font in food packs

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The Food Safety and Standards Authority of India (FSSAI) has approved the proposal at its latest meeting

Packaged food items that are sold in India will now have to display information about total sugar, salt and saturated fat content in bold and relatively bigger fonts. 

In a country that is on the cusp of a diabetes and metabolic diseases epidemic, packaged food items have penetrated every social strata. The move, the government hopes, will foster a certain level of consciousness among consumers to help them decide better.

The decision to approve the amendment in the Food Safety and Standards (Labelling and Display) Regulations, 2020 regarding Nutritional information labelling was taken in the 44th meeting of the Food Safety and Standards Authority of India (FSSAI), held under the chairmanship of Shri Apurva Chandra, Chairperson, FSSAI. 

The draft notification for the said amendment would now be put in the public domain for inviting suggestions and objections.

The information regarding per serve percentage (%) contribution to Recommended Dietary Allowances (RDAs) would be given in bold letters for total sugar, total saturated fat and sodium content. Regulation 2 (v) and 5(3) of FSS (Labelling and Display) Regulation, 2020 specifies requirements to mention serving size and nutritional information on the food product label, respectively.

There are hopes that the display of this information will eventually contribute towards efforts to combat the rise of Non-Communicable Diseases (NCDs) and promote public health and well-being. The prioritisation of the development of clear and distinguish labelling requirements would help in the global effort to combat NCDs.

FSSAI has been issuing advisories from time to time to prevent false and misleading claims. These include advisories sent to e-commerce website for removal of the term ‘Health Drink’ as it is not defined or standardized anywhere under the FSS Act 2006 or rules/regulations made thereunder, apart from directive mandating all Food Business Operators (FBOs) to remove any claim of ‘100% fruit juices’ from the labels and advertisements of reconstituted fruit juices, the use of the term wheat flour/ refined wheat flour, the advertisement and marketing of ORS along with prefix or suffix, nutrient function claim for multi-source edible vegetable oils etc. These advisories and directives are issued to prevent misleading claims by FBOs.

Obesity may improve survival chances in some forms of head and neck cancer

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Researchers looked at survival in some cancer patients after immunotherapy and found that obese patients often fare better

Obese patients of some head and neck cancers have better chances of survival post immunotherapy than non obese patients, researchers have found. The findings mirror earlier revelations in some other forms of cancer.

Researchers from Thomas Jefferson University, Pennsylvania and Vanderbilt University Medical Center Tennessee looked at national, multicenter cohort of 166 patients with head and neck squamous cell carcinoma (HNSCC) and came to this conclusion. They reported their findings in the journal Jama Otolaryngology – Head and Neck Surgery. 

“Using population-level data for patients with HNSCC treated with ICIs (immune checkpoint inhibitors), these results suggest that having obesity was associated with improved 6-month, 3-year, and 5-year OS (overall survival) compared with having normal BMI. Additionally, obesity was associated with decreased gastrostomy and tracheostomy tube dependence compared with normal BMI. Further investigation is required to understand the mechanism of these findings.” Immune checkpoint inhibitors are a type of immunotherapy that blocks a physiological mechanism that ensures that blood cells responsible for the body’s immunity do not end up killing the body’s own cells.

Earlier, researchers had reports better survival rates for obese patients who were suffering from renal cancer and some skin cancers. There have also been other and bigger studies in the United Kingdom that had independently reached the conclusion that obese patients with head and neck cancers have worse survival rates but the current study pertains specifically to patients who had received immunotherapy.

Researchers looked at survival in some cancer patients after immunotherapy and found that obese patients often fare better

Obese patients of some head and neck cancers have better chances of survival post immunotherapy than non obese patients, researchers have found. The findings mirror earlier revelations in some other forms of cancer.

Researchers from Thomas Jefferson University, Pennsylvania and Vanderbilt University Medical Center Tennessee looked at national, multicenter cohort of 166 patients with head and neck squamous cell carcinoma (HNSCC) and came to this conclusion. They reported their findings in the journal Jama Otolaryngology – Head and Neck Surgery. 

“Using population-level data for patients with HNSCC treated with ICIs (immune checkpoint inhibitors), these results suggest that having obesity was associated with improved 6-month, 3-year, and 5-year OS (overall survival) compared with having normal BMI. Additionally, obesity was associated with decreased gastrostomy and tracheostomy tube dependence compared with normal BMI. Further investigation is required to understand the mechanism of these findings.” Immune checkpoint inhibitors are a type of immunotherapy that blocks a physiological mechanism that ensures that blood cells responsible for the body’s immunity do not end up killing the body’s own cells.

Earlier, researchers had reports better survival rates for obese patients who were suffering from renal cancer and some skin cancers. There have also been other and bigger studies in the United Kingdom that had independently reached the conclusion that obese patients with head and neck cancers have worse survival rates but the current study pertains specifically to patients who had received immunotherapy.

Every third Indian has fatty liver; diabetes and metabolic disorders follow says minister

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Union Minister Dr. Jitendra Singh launched the Indo-French Liver and Metabolic Disease Network (InFLiMeN)

Every third Indian has fatty liver, which predates Type 2 Diabetes and other metabolic disorders, Union Minister Dr Jitendra Singh said on Friday. He was speaking at the launch of the Indo-French Liver and Metabolic Disease Network (InFLiMeN) a virtual node to prevent and cure metabolic liver diseases at Institute of Liver and Biliary Sciences.

Dr Singh is a diabetologist by training. He said: “Both the Indian subcontinent and Europe are attributable to changes in lifestyle, diet and importantly metabolic syndromes such as diabetes and obesity which have contributed to a significant rise in NAFLD. Nearly 1 in 3 Indians has fatty liver. While in the West, most NAFLD is associated with obesity, intriguingly in the Indian subcontinent, NAFLD occurs in about 20% of non-obese patients.” He added: “There is a considerable burden of alcoholic liver disease (ALD) in India and France.” He said that both NAFLD and ALD exhibit a very similar progression from steatosis to steatohepatitis, cirrhosis and HCC.

Dr. Jitendra Singh advised that a joint multi-disciplinary collaborative program like InFLiMeN is urgently needed to understand the development, progression and possible management of liver diseases using a comprehensive omics approach for biomarker discovery.

Emphasizing on the co-operation and collaboration of both the Government and Private sector to provide best services to citizens and promote ease of healthy living. He also highlighted the government’s initiatives and policies aimed at supporting and improving the healthcare system. He said, “A large population in India is affected by metabolic disorders and we need India specific interventions as our phenotype is different.” We need Indian Solutions for Indian problems, he added.

He appreciated Prof. Abhay Karandikar, Secretary, DST along with the department and Indo-French Centre for the Promotion of Advanced Research (CEFIPERA) for taking this novel approach proposed by ILBS.

The Minister congratulated Dr. Shiv Kumar Sarin and his team along with the French collaborators. He also directed them to find remedies for the metabolic disorders in a low cost and high output manner. 11 French and 17 Indian doctors work jointly in this node.